✔ Non-healing wounds including diabetic foot ulcers, non-healing surgical wounds

✔ Delayed radiation injury such as injury to the bladder or gut after cancer therapy)

✔ Sudden sensorineural hearing loss (idiopathic)

✔ Exceptional blood loss

✔ Air or gas embolism

✔ Carbon monoxide poisoning and/or cyanide poisoning (from inhaling smoke or car exhaust)

✔ Gas gangrene (clostridial myositis and myonecrosis)

✔ Crush injury, compartment syndrome, and other acute traumatic ischemias (such as frostbite)

✔ Decompression sickness ("the bends")

✔ Intracranial abscess

✔ Necrotizing soft tissue infections (flesh eating disease)

✔ Osteomyelitis (bone infection)

✔ Skin grafts and flaps (compromised)

✔ Thermal burns